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	Provedor de dados BJMBR (2) Autor Lima,E.N.P. (2) Carneiro,C.R.W. (1) Carvalho,S.M.T. (1) Collins,J.B. (1) Fontes,C.M. (1) Iyeyasu,H. (1) Maciel,M.S. (1) Makdissi,F.B. (1) Moraes,D.W. (1) Mourão Netto,M. (1) Osório,C.A.B.T. (1) Perina,A.L. (1) Pimentel,A.M. (1) Prado,I.B. (1) Soares,F.A. (1) Mais... Palavra-chave Breast neoplasms (1) Carcinoembryonic antigen (1) Colorectal carcinoma (1) Completion axillary dissection (1) Immunoscintigraphy (1) Monoclonal antibody (1) Sentinel lymph node (1) Sentinel lymph node biopsy (1) Technetium-99m (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2010 (1) 1999 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Evaluation of an anti-carcinoembryonic monoclonal antibody suitable for immunoscintigraphy BJMBR Moraes,D.W.; Lima,E.N.P.; Prado,I.B.; Carneiro,C.R.W.. An anti-carcinoembryonic antigen (CEA) monoclonal antibody (mAb 6D1.1) was evaluated in vitro and in vivo to determine its suitability as a tracer for immunoscintigraphy of colorectal carcinomas. Determination of mAb affinity for CEA showed a constant of association of 0.63 ± 0.11 x 109 M-1. Binding of technetium-99m (99mTc)-6D1.1, labeled by a direct method, to human cultured lineages was highly specific. Binding to only CEA-positive LS-174T cells resulted in a saturable curve inhibited by pre-incubation with unlabeled mAb. No binding at all was observed for the human lineages MeWo (melanoma) or ZR75-30 (breast carcinoma), neither of them expressing CEA cells. Intravenous injection of 99mTc-6D1.1 into nude mice xenografted with human LS-174T tumors... Tipo: Info:eu-repo/semantics/article Palavras-chave: Monoclonal antibody; Carcinoembryonic antigen; Colorectal carcinoma; Immunoscintigraphy; Technetium-99m. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000800006 Sentinel node biopsy in breast cancer: results in a large series BJMBR Carvalho,S.M.T.; Mourão Netto,M.; Lima,E.N.P.; Pimentel,A.M.; Makdissi,F.B.; Osório,C.A.B.T.; Maciel,M.S.; Iyeyasu,H.; Collins,J.B.; Fontes,C.M.; Perina,A.L.; Soares,F.A.. Sentinel lymph node biopsy (SLNB) is an appropriate method for the evaluation of axillary status in cases of early breast cancer. We report our experience in treating cases evaluated using SLNB. We analyzed a total of 1192 cases assessed by means of SLNB from July 1999 to December 2007. SLNB processing was successfully completed in 1154 cases with the use of blue dye or radiolabeled 99mTc-Dextran-500, or both. Of these 1154 patients, 857 were N0(i-) (no regional lymph node metastasis, negative immunohistochemistry, IHC), 96 were N0(i+) (no regional lymph node metastasis histologically, positive IHC, no IHC cluster greater than 0.2 mm) and 201 were N1mi (greater than 0.2 mm, none greater than 2.0 mm). Most of the tumors (70%) were invasive ductal carcinomas... Tipo: Info:eu-repo/semantics/article Palavras-chave: Breast neoplasms; Sentinel lymph node; Sentinel lymph node biopsy; Completion axillary dissection. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000600011 Registros recuperados: 2 Primeira ... 1 ... Última

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